Thymelaeaceae
©The
World Botanical Associates Web Page
Prepared by Richard W. Spjut
December 2004
Dirca occidentalis
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Dirca occidentalis
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Dirca occidentalis
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Antileukemic and Cytotoxic Activity (Mohammed et al., J. Pharm. Sci.) |
Badawi M. M., S. S. Handa, A. D. Kinghorn, G. A. Cordell GA and N. R. Farnsworth. 1983. Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (Thymelaeaceae). J. Pharm. Sci. 72(11): 1285–1287. “Two antileukemic daphnane esters, Pimelea factor P2 (I) and the new compound dircin (II), were isolated from the twigs and flowers of Dirca occidentalis A. Gray (Thymelaeaceae). Three lignans, (-)-medioresinol (III), (+)-syringaresinol (IV), and (-)-lariciresinol (V), as well as the coumarin daphnoretin (VI), were found to be additional cytotoxic constitents of this taxon.” |